Skin Tight Breast Firming Lotion from Nourish Skin Care is specifically
formulated for sensitive breast skin, firms and tightens skin, reduces
sagging, lifts and defines.
loose or sagging skin from weight loss, childbirth, nursing, or aging.
Active ingredients penetrate deep into dermal layers to promote healthy
skin development, infuse hydration and moisture and firm and tighten
loose skin on around the breasts.
Skin Tight Breast Firming Lotion combines a polypeptide complex, to
reduce saggy skin and rejuvenate elasticity. A proven active ingredient
improves smoothness to the skin making your bust softer and more supple.
Improved collagen and dermal layer strength lifts and adds definition
to sagging providing increased firmness while reducing excess fluids
that can lead to excessive softening and loss of "perkiness".Green
Tea extract and Emu Oil provide penetrating preservation of sub-dermal
tissue and increase skin cell membrane health and turnover - helping to
tighten and providing long-term breast health.
3000 as a synergistic combination
Matrixyl 3000 combines palmitoyl
oligopeptide and palmitoyl tetrapeptide-7 not just because two active
ingredients are better than one. According to the Sederma corporation, these
two peptides produce a synergy when used together, i.e. the skin benefits of
such combination are greater than what one would expect if each agent's effects
were independent of each other.
oligopeptide (Pal-GHK) is one of the two active ingredients in Matrixyl 3000.
It consists of a short chain of three amino acids (a.k.a. GHK peptide or
glycine-histidine-lysine) connected to palmitic acid. Palmitic acid is a fatty
acid added to improve the peptide's oil solubility and thus skin penetration.
The peptide GHK is a fragment of type I collagen molecule and is believed to
serve as a biological indicator of increased degradation of the skin matrix.
Indeed, when collagen is degraded, more of its small fragments get created in
the body, including GHK. Furthermore, GHK is believed to stimulate the feedback
loop triggering the synthesis of new collagen as well as other components of
the skin matrix. When the key skin matrix-producing cells (fibroblasts) detect
increased levels of GHK, they "assume" that the skin matrix is being
lost at a higher rate and begin synthesizing it more vigorously. Thus, Pal-GHK
(a version of GHK designed for better skin penetration) is intended to stimulate
skin matrix replenishment via topical application, leading, presumably, to
wrinkle reduction, skin firming and other benefits.
interesting point about the GHK is that it is a part of another well known skin
care ingredient, the copper peptide Cu-GHK. Copper peptides are known to
improve wound healing, activate skin remodeling, improve the structure of skin
matrix, reduce scarring and exert other beneficial effects on the skin. The
skin benefits of copper peptides are relatively well researched and
established. In fact, most of the research showing the benefits of copper
peptides has been done using Cu-GHK, which consists of the copper atom (in the
ionized form) bound to the GHK peptide.
light, we can hypothesize that Pal-GHK may act at least partly via the same
mechanism as Cu-GHK. At the first glance, this appears unlikely because the
benefits of copper peptides are believed to be contingent on their copper
component. However, it is possible that the addition of the palmitic acid to
the GHK increases its skin concentration so much that even the normally low
levels of copper in the skin suffice to activate it. It is also conceivable
that many of the effects of Cu-GHK are due to the GHK peptide rather than
copper and can be reproduced using a highly penetrating version Pal-GHK alone.
Palmitoyl tetrapeptide-7 (Pal-GQPR)
Palmitoyl tetrapeptide-7 (Pal-GQPR)
is another active ingredient in Matrixyl 3000. (It was also formerly known and
marketed as palmitoyl tetrapeptide-3.) Palmitoyl tetrapeptide-7 consists of a
short chain of four amino acids (a.k.a. GQPR peptide or
glycine-glutamine-proline-arginine) connected to palmitic acid. Palmitic acid
is a fatty acid added to improve the peptide's oil solubility and thus skin
Palmitoyl tetrapeptide-7 is believed
to work by reducing the production of interleukin-6 (IL-6) by the the key skin
cells, keratinocytes and fibroblasts. IL-6 is a molecule that promotes
inflammation, which, in turn, leads to faster degradation of the skin matrix
and thus contributes to the development of wrinkles and loss of skin firmness
and elasticity. By reducing the levels of IL-6 and possibly other inflammation
mediators, palmitoyl tetrapeptide-7 is thought to slow down the degradation of
the skin matrix and may also stimulate its replenishment.